Med Bull Sisli Etfal Hosp. 2001; 35(2): 22-26

Bone tumors in adolescents and young adults

Mehtap D. Çalýþ, Öznur Aksakal, Yusuf Baþer, Alpaslan Mayadaðlý, Oktay Ýncekara
Þiþli Etfal Eðitim ve Araþtýrma Hastanesi, Radyasyon Onkolojisi Kliniði, Ýstanbul

PURPOSE: This study evaluates retrospectively those patients diagnosed with adolescent and young adult bone tumors whose applied to our clinic between 1989-1999.
RATIONALE AND METHOD: Between 1989-1999, 50 patients, aged between 15-30, with bone tumors diagnosis applied to our clinic. 37 were male and 13 were female (Men/Women: 2.8) 20 patients had osteosarcoma (40%), 13 had Ewing‘s sarcoma (26%), 5 had hasta fibrous histiocytoma malignant (10%). The most frequent tumor localization was the lower extremity (25 patients, 50%). 9 patients were at stage 4b (18%), 14 were at stage 4a (28%), 22 patients were at stage 2b (44%) and 5 patients were at stage lb (10%). Lung metastasis was the most frequent one. 38 patients (76%) received systemic chemotherapy and 32 patients (64%) received radiotherapy. The average survival period was 18 months ( Range 2-66 months).
RESULTS: The factor effecting survival was found as a localization of metastdsis.

Keywords: Bone tumors, adolescent and young adult, surgery, radiotherapy, chemotherapy, osteosarcoma, Ewing‘s sarcoma.

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Adölesanlarda ve Genç Eriþkinlerde Kemik Tümörleri

Mehtap D. Çalýþ, Öznur Aksakal, Yusuf Baþer, Alpaslan Mayadaðlý, Oktay Ýncekara
Þiþli Etfal Eðitim ve Araþtýrma Hastanesi, Radyasyon Onkolojisi Kliniði, Ýstanbul

AMAÇ: Bu çalýþmada 1989-1999 tarihleri arasýnda kliniðimize müracaat eden adölesan ve genç eriþkin genç eriþkin dönemi kemik tümörü tamlý hastalar retrospektif olarak deðerlendirilmiþtir.
GEREÇ VE YÖNTEM: 1989-1999 tarihleri arasýnda 15-30 yaþ arasý kemik tümörü tanýlý 50 hasta kliniðimize müracaat etmiþtir. Erkek hasta 37, kadýn hasta 13 idi.( Erkek / Kadýn: 2.8). 20 hasta osteosarkom (%40), 13 hasta Ewing sarkomu (%26), 5 hasta malign fibröz histiositom‘dur (%10). Tümörün en sýk yerleþim yeri; 25 hasta (%50) ile alt ekstremdedir. 9 hasta stage 4b (%18), 14 hasta stage 4a (%28), 22 hasta stage 2b (%44), 5 hasta stage lb dir. En sýk akciðer metastazý görülmüþtür. Hastalarýn 38‘ine (%76) sistemik kemoterapi, 32‘sine (%64) radyoterapi uygulanmýþtýr. Ortalama sað kalým süresi 18 aydýr (2-66 ay).
SONUÇ: Sað kalým üzerine en etkili faktör olarak; uzak metastazýn lokalizasyonu bulunmuþtur.

Anahtar Kelimeler: Kemik tümörleri, adölesan ve genç eriþkin, cerrahi, radyoterapi, kemoterapi, osteosarkom, Ewing sarkomu.

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