7 - The comparison of recombinant fsh and highly purified FSH regimens in chronic anovulatory cases
Ayşe Aydın, Ahmet Varolan, Asuman Sevük, İnci Davas
Objective: In the cases of chronic anovulation with policystic ovary disease who had been resistant to clomiphene citrate treatment, the effectiveness of hpFSH and rFSH were compared.
Study Design: Among the 20 patients diagnosed as PCOS, infertility treatment scheduled with rFSH and hpFSH foi- induction of ovulation and insemination in two groups (n-10). Ovulation monitorised by transvaginal ultrasonography in the day after intervals. At the period of treatment 3rd day of the cycle and ovulation day serum hormon prophiles compared.
Results and conclusion: When two groups were compared, for clomiphene citrate resistant chronic anovulatory PCOS patients both the recombinant technology products and highly purified FSH preparations were good alternatives in the ovulation induction. However statistical significance were present for serum hormon values but not for the occurance of ovulation.
Keywords: Polycystic ovary, anovulation, rFSH, hpFSH.
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