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          VOLUME 43 / ISSUE 3


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6 - Cerebral venous thrombosis in a patient with heterozygous methylenetetrahydrofolate reductase (C677T) polymorphism

Sinan Mahir Kayıran, Bülent Zülfikar

Venous thromboembolism is decribed as a multifactorial disorder including both congenital and acquired risk factors and generally detected in elder patients. Although cerebral venous thrombosis (CVT) is associated with substantial mortality and morbidity, its causes in children have not been intensively investigated, mainly because it occurs at a low frequency (0.67 per 100000 children). But the reports of thrombotic events in children are increasing. Methylenetetrahydrofolatereductase (MTHFR) C677 T polymorphism has been detected as an important role in inherited thrombophilia in recent years. In this article we report a child with cerebral venous thrombosis and heterozygous methylenetetrahydrofolatereductase (MTHFR) C677 T polymorphism after otomastoiditis.

Keywords: Cerebral venous thrombosis MTHFR (C677T) Polymorphism Otomastoiditis Child Patient

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