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10 - The preliminary results of radio-chemotherapy in locally advanced gastric and pancreas cancer
Fatma Ataman, Vildan Şimşir, Cenk Ahmet Şen, Hakan Bozcuk, Mehmet Öğüş, Okan Erdoğan, Burhan Savaş
Between February 2000 and November 2003 we treated 22 stomach and 10 pancreas cancer patients with definitive, adjuvant or palliative radiation and concurrent chemotherapy in the Department of Radiotherapy, Akdeniz University. Median age of the gastric cancer patients was 53 (27-69); 15 were men and 7 were women. Median age of the patients with pancreas cancer was 60 (48-78); 6 were men and 4 were women. The gastric and pancreas cancer patients received external beam radiation with linear accelerator to a median total dose of4729 (4140-5400) cGy and 4896 (4140-5400) cGy, respectively. The gastric and pancreas cancer patients received 5FU+leucovarin and 5FU, respectively. Median follow- up of the gastric cancer patients was 20,6 months (5-46). Of the 22 patients with gastric cancer, fourteen patients (64%) died due to local-regional recurrence + metastasis, 4 patients (18%) were alive with local-regional recurrence, and the other 4 (18%) were alive free of disease. Median follow-up of the patients with pancreas cancer was 14,1 months (6-22). Of the 10 patients with pancreas cancer, 8 (80%) died due to local-regional recurrence, and 2 (20%) died due to local- regional recurrence + metastasis. A multidisciplinary treatment approach for pancreas and stomach cancer, where modern radiotherapy techniques are used to minimize normal tissue complications was established in our institute, and the preliminary results were presented in this study.
Keywords: Pancreas cancer, stomach cancer, radiotherapy, chemotherapy.
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