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2 - Evaluation of carotid intima media thickness in patients who have undergone radiation therapy for head and neck malignancy
Nuran Yılmaz, A. Deniz Kahraman, A. Nedim Kahraman, Aydın Ağdere, İrfan Çelebi, Muzaffer Başak
Objective: The aim of this study was to investigate radiotherapy effects on carotid intima-media thickness in patients with head and neck tumor.
Material and methods: 30 patients (aged between 20 and 74 years) and a group of 30 age and sex matched controls were studied by ultrasound. The intima-media thickness (IMT) at the far wall of the CCA (common carotid arter) was measured three times and the average value taken in each subject. The IMT of both groups were compared. Risk factors for IMT, including hypertension, smoking, hyperglycemia, history of cerebrovascular accidents and cardiovascular disease were also studied.
Results: The mean value of carotid intima-media thickness in patients with the head and neck cancer group (1.8+1-1.3 mm) was greater than that in normal controls (0.7+1-0.2 mm) and there was statistically significant difference between them (p<0.05). There was no statistically significant difference between the IMT in the right and left CCA within each group of patients (p>0.05). Among all other risk factors, there was no statistically significant difference between two groups (p >0.05).
Conclusion: The findings suggest that patients with irradiation have increased carotid IMT.
Keywords: ultrasonography, intima-media thickness, carotid arteries
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