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8 - Giving up smoking and changes in lipid profile
Çiğdem Yazıcı Ersoy, Kerim Küçükler, Ülkü Kerimoğlu, Murat Kemahlı, Sertaç Öztürk, Fatih Borlu
Purpose: Cigarette is one of the independent and alterable risk factors of Coronary Artery Disease. Despite the importance of this matter has been well comprehended and efforts against cigarette smoking performed in developed societies, it is still an important societal problem. Today, a clear data in our hand is that cigarette smoking is an independent risk factor which can affect the lipid metabolism.In this study .changes in lipid profile in relation to time by giving up smoking have been evaluated.
Materials and methods: This study was conducted on 60 people who smoke cigarettes and are willing to give up smoking out of our hospital staff (physician, nurse and assistant health personnel) and their relatives. Total cholesterol and HDL- cholesterol levels of the individuals were determined in blood samples taken in the morning after 12 to 14 hours of fasting. And the ratios of total cholesterol to HDL- cholesterol of all the subjects were calculated. These individuals were assessed for lipid profiles again I month and 3 months later.
Findings: Mean age, smoking period and daily cigarette consumption of the subjects in our study were 40,3 ± 11,4 years, 16,7 ± 7,0 years and 21,9 ± 6,07 cigarettes per day respectively. There was no significant difference between total cholesterol levels tested before and 1 month and 3 month after giving up smoking. On the other hand, in HDL- cholesterol levels, a statistically highly significant increase was detected / month after giving up smoking compared to before giving up. And there was no statistically significant difference in HDL- cholesterol levels of the individuals between 1 month after and 3 months after giving up smoking.
Conclusion: Cigarette smoking causes serious alterations in lipid metabolism. However the effect of smoking is not permanent. Temporary depressive effect on 11DL- cholesterol levels begins to recover in 30 days after stopping cigarette smoking.
Keywords: Giving up smoking, serum total cholesterol- HDL cholesterol levels, 30 days
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