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2 - Seroprevalance of hepatitis a in children between 2 and 15 years old
Esra Deniz Papatya, Tülay Olgun, Mahmut Ekici, Nafiye Urgancı, Gül Özçelik, Deniz Çakır
Objective: Hepatitis A virus (HAV) infection especially acquired during childhood.This infection still an important health problem in our country. We studied anti-HAV Ig G antibody levels in the members of different age groups and different socioeconomic status groups children and adolescents that administrated Şişli Etfal Hospital Pediatrics policlinics for determining anti-HAV Ig G seroprevalance and Hepatitis A vaccination strategy.
Study Design: During the period of April 2002-September 2002, 606 children and adolescents administrated pediatrics policlinics for any reasons that tested for anti-HAV Ig G antibody. None of them hadnt jaundice. Blood samples were tested by micro enzyme linked immunosorbent assay (ELİSA) . We used Bio-Rad kit to detect anti-HAV Ig G .
Results: 319 (%52,6) patients were seropositive. 287 (%47,4) patients were seronegative. In the age group of 2-3 years old seropositivity was the most decreased. %34,7 patient in this age group was seropositive. In the 14-15 age group seropositivity rate was the most increased. Seropositivity rate of this group was %88.
Seropositivity rate is inceased by many factors such as low level socioeconomic status, older age groups, families which have lots of members (p<0.001). No seropsitivity difference found between male and female groups (p>0.05). When the socioeconomic status got become worst anti- HAV IgG seropositivity was increased (p<0.01).
Conclusions: Studies which were done in our western areas shows that over % 80 of school age children are sensitive for HAV infection.In our study children who were at preschool age are sensitive for hepatitis A virus infection. In this groups sensitivity rate is %50-55. In our opinion Hepatitis A vaccine may be advised to the seronegative preschool age groups.
Keywords: Hepatitis A, seroprevalance, age groups.
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