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6 - The relationship between severe ischemia and endogenous sex hormone levels in postmenopausal women with coronary artery disease
Fatih Borlu, Ali Özgür Öztürk, Kerim Küçükler, Songül Peker,Nihat Özer
Objective: This study prospectively evaluated the association between endogenous serum sex hormone levels and the degree of myocardial ischemia in postmenopausal women with established as clinical and laboratory coronary heart disease.
Material and Methods: 94 women with coronary artery disease and 46 healthy women were included in the study.These groups were enrolled as clinic,biochemical,angiographic,exercise test and SPECT findings. The two groups were seperated as normal,mild- moderate and severe ischemia according to the results of the tests.Serum estradiol and free testosteron levels were measured in the last two groups and compared.
Results: The estradiol levels were significantly lower than other groups in the severe ischemic group(p<(),01). Free testosteron levels were significantly higher than other groups in the severe ischemic group(p=(),()2).No difference was found in total testosteron levels between all groups
Keywords: Coronary artery disease,postmenopausal women,endogenous sex hormones.
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