The publication of University of Health Sciences Istanbul Sisli Hamidiye Etfal Application and Research Center.


Online article submission system has been turned over to eJManager. We kindly request you to submit your current article or new articles via eJManager system

          VOLUME 36 / ISSUE 1


The Journal is Indexed in


9 - Effects of high dose vitamin A supplementation on the treatment of lower respiratory tract infections in infants

Cengiz Asilsoy, Feyzullah Çetinkaya, Merih Evrüke, Metin Uysalol, Günsel Kutluk

Objective: In this study the affect of a high dose of vitamin A as adjuvant treatment for cases with acute lower respiratory tract infection was tested in infants.

Study design: We conducted a randomized, double-blind, placebo- controlled clinical trial of high-dose vitamin A supplements among children aged 2 to 24 months (N - 40) admitted to hospital with bronchopneumonia or bronchiolitis. Vitamin A (100,000 IU for children less than 1 year of age, and 200,000 IU for older children) or placebo were given to the children in addition to standard treatment regimens . The children were assessed with clinical findings four times a day and with laboratory tests at the begining and fifth days of the treatment.

Results: There were not significant differences between placebo and vitamin A groups in the rate of normalization of clinical and laboratory findings.

Conclusion: These data show that supplementation of high doses of vitamin A has no additional advantage in the treatment of lower respiratory tract infections of infants.

Keywords: Lower respiratory tract infections, vitamin A

To read full article click


Home Page       Editorial       Editorial Board       Advisory Board       Information for Authors       Contact       Archive

Copyright ® 2011 Sisli Etfal Hastanesi Tıp Bülteni