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          VOLUME 35 / ISSUE 4

The Journal is Indexed in

14 - Rosai-Dorfman disease affecting the subglottic area and submandibular lymph nodes

Emine Yetkin , Deniz Özcan, Pınar Özay, Cem Çomunoğlu, Yalçın Varnalı, Halil Akbörü

Objective : Rosai-Dorfmann Disease ( Sinus histiocytosis with massive Iymphadenopaty-SHML) is a rare, idiopathic, histiocytic proliferative disorder that most commonly involves the cervical lymph nodes. The typical clinical features of this disease include bilateral painless lymph node enlargement, fever, leucocytosis, elevated eiythrocyte sedimentation rate, policlonal hypergammaglobulinemia. Generally, this is a benign reactive disorder, have an indolent clinical course; but have a highly variable biological behaviour. Here we report a case of Rosai Dorfmann Disease affecting the subglottic area and submandibular lymph nodes and discussed in the view of the literature.

Keywords: Subglottic area, submandibular lymph nodes, sinus histiocytosis, massive lymphadenopathy.

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