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12 - Results of treatment of small cell lung cancers at our clinic
Özlem Maral, Didem Karaçetin, Saliha Peksu, Ahmet Uyanoğlu, Öznur Aksakal, Oktay İncekara
Objective: Our purpose was to evaluate the results of our treatments of patients with small cell lung cancer between the years 1989-1997.
Study Design: We studied retrospectively 112 patients who were treated at our clinic between 1989-1997 with small cell lung cancer. All the patients were followed-up for more than 6 months and results of treatment methods were compared in relation to their corresponding stages. Ki-square statistical method was utilized in this study.
Results: 107 patients were male and 5 patients were female. Primary tumoric cells were found to be with 58 patients in right lung and with 54 patients in the left lung. 62 patients had métastasés, 9 patients had multiple organs métastasés and the most common métastasés were observed to be in brain. Chemotherapy and radiotherapy was used with 25 patients (64.2%9 with limited-spread of carcinoma, and with 31 patients (42.4%) in advanced-spread of disease. 56 patients after chemo-radiotherapy had 7.4 months of survival rate without disease, general survival rate was calculated to be 13.8 months. The other 56 patients who had only chemotherapy, survived for 6.1 months; and with these patients general survival rate was 9.8 months. Between these 2 methods statistical comparison calculated to be (p:0.005). patients shown limited -spread responded with 63.5%, advanced-spread was 22.1%.
Conclusion: With small cell lung cancer, application of multiagent systemic chemotherapy, Chemotherapy¦cLocal radiotherapy found to be increasing survival rates.
Keywords: Small cell lung cancer, radiotherapy, chemotherapy
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