The publication of University of Health Sciences, Istanbul Sisli Hamidiye Etfal Medical Practice and Research Center

Online article submission system has been turned over to eJManager. We kindly request you to submit your current article or new articles via eJManager system

          VOLUME 35 / ISSUE 2

The Journal is Indexed in

6 - Comparisons of oral calcium, high Dose vitamin D and combination of these in the treatment of nutritional in children

Günsel Kutluk, Feyzullah Çetinkaya, Muzaffer Başak, Merih Evküre, Metin Uysalol, Cengiz Asılsoy

Objective: Nutritional rickets still remains a common child health problem ind Turkey and many other developing countries. Although vitamin D deficiency is accepted as the basic problem underlying the disease, some others postulate that a deficiency of dietary calcium, rather than vitamin D, is often responsible for the nutritional rickets in sunny countries. We conducted a placebo-controlled study to determine the best treatment form in nutritional rickets in children from a lower socioecenomic group in İstanbul.

Study design: We enrolled 45 infants (aged 6-30 months) with rickets in a randomized, doble-blind, controlled trial of 4 weeks of treatment with vitamin D (300,000 U i.m.), calcium, phosphorus and alkaline phosphatase and used a 10-point radiographic score to assess the response to treatment.

Results : Treatment produced an increase in serum calcium and a decrease in alkaline phosphatase concentration in all three groups, but the most important increase was reached in vitamin D plus calcium group.

Conclusions: Vitamin D deficiency appears to be the primary etiologic factor of rickets in our children with rickets but a better response to treatment with vitamin D or in combination with calcium were taken than to treatment with vitamin calcium alone.

Keywords: Rickets, Vitamin D, Avitaminosis.

To read full article click

Home Page       Editorial       Editorial Board       Advisory Board       Information for Authors       Contact       Archive

Copyright ® 2011 Sisli Etfal Hastanesi Tıp Bülteni