The Journal is Indexed in
10 - The Effects Of Morphine-Bupivacaine Combination On Postoperative Analgesia And Early Mobilisation
G. Ulufer Sivrikaya, O. Tuğrul Eren, Mustafa Tekkeşin, Ayşe Hancı, Ünal Kuzgun
Objective: We performed a randomised, double-blind controlled study in 40 patients undergoing knee arthroscopy to evaluate the effects of intraarticular (morphine- bupivacaine) combination on postoperative pain treatment and early mobilisation.
Study Design: The patients in group I received 3 mg of morphine-75 mg 0.25% bupivacaine combination in 30 ml NaCl solution intraarticulary while those in group II received 30 ml saline alone at the end of the operation. Postoperative pain was assessed at 1., 4., 2.,8.,12. and 24. hours by Visual Analogue Scale (VAS) and by VAS and Walking Scale (WS) at 2.-7. days. Need for analgesic drugs, time to walking without crutches and side effects were recorded.
Results: VAS values were lower in group I than in group II at all hours postoperatively. Need for analgesic drug was occurred for group II at 4. hours postoperatively. VAS and VPS values were significantly lower in group I than group II. at postoperative 2.-7. days. Total analgesic consumption was significantly higher in group II than group I. Time to return walking without crutches was significantly shorter in group I than group II. There was not any significant difference between the groups about side effects.
Conclusions: We concluded that; the combination of intraarticular morphine and bupivacaine provides effective pain control and has a positive effect on returning to normal activities following arthroscopic knee surgery.
Keywords: Intraarticular, morphine, bupivacaine, analgesia, early mobilisation
To read full article click