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          VOLUME 34 / ISSUE 3

The Journal is Indexed in

8 - Comparison of hemodynamic parameters and recovery characteristics of propofol and etomidate in tiva

İnci Paksoy, Sibel Oba, Surhan Özer Çınar, Gülay Aşık Eren, Oya Hergünsel

OBJECTIVE : In this study, we aimed to compare the effects of propofol and etomidate TIVA on hemoynamic parameters and recovery time.

STUDY DESIGN: Thirty patients of ASA I, II were divided into two groups. In Group I, 2 mgr/kg fentanyIIV was used before induction and anesthesia was induced with 2- 2.5 mg/kg propofol and 0.1 mg/kg vecuronium. During maintenance of anesthesia propofol was infused at a rate of 10 mg/kg/h during first 10 minutes, 8 mg/kg/h during second 10 minutes and 6mglkglh thereafter. In addition 2 mgr/kg/h fentanyl was infused in %3002% 70 air mixture. Vecuronium was used when needed. Group II received the same anesthesia with etomidate 0.3 mg/kg at induction and 20 *gr/kg/min at maintenance. Before and after induction, after intubation, just before surgical intervention, preoperatively (at every 5 minutes) and after extubation systolic, diastolic, mean arterial blood pressure and heart rate of all patients were noted. In the postoperative period the patients were observed for the recovery and wake up scores.

RESULTS: There were significant decrease and increase in hemodynamic parameters in Group I when compared with other groups (p<0.05). Time to recovery was longer in Group 11 than the other groups. (p<0.05).

CONCLUSION: Finally, TIVA with etomidate is more stable hemodynamically than propofol, but recovery time is shorter in propofol TIVA.

Keywords: TIVA, propofol, etomidate, hemodynamic stability, recovery.

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