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11 - Our Results External Radiothrapy in Oligodendrogliomas
Alpaslan Mayadağlı, Mehtap Dalkılıç Çalış, Oktay İncekara
PURPOSE: Oligodendrogliomas is of 1-5% of primary intracranial tumors in adults. Adjuvant radiotherapy is suggestedfollowing maximal surgical resection. This study retrospectively evaluates the oligodendroglioma cases who applied to our clinic in 10 years.
MATERIALAND METHOD: 615 cases with intracranial tumors applied to our clinic between 1985-1999. 14 patients had oligodendrogliomas (2.27%). 6 werefemale and 8 were male. (Female!Male: 314). The most common age range was endroglioma-astrocytoma. in ali patients the tumor had supratentorial localization. The tumor was in the frontal lobe in 5, parietal lobe in 4, parietooxypital lobes in 3, temporal lobe in 1, and frontotemporoparietal lobes in 1 patient. According to Karnofsky Performance Scale (KPS); 6 patients were at 90%, 5 were at 70%, 1 was at 50%, 1 was at 30%, 1 was at 10% status. The mostfrequent surgery was subtotal resection (7 patients-50%). 4 patients were at stage 2a, 7 at stage 2b, 3 at stage 4. 12 patinets ad total cranial, 2 had partial cranial radiotherapy, 11 patients had postoperative radiotherapy, 3 inoperable patients had radiotherapy following biopsy. 3 patients had palliative total cranial radiotherapy of 30 Gy! 10 fraction due to low KPS, 9 had total cranium+boost radiotherapy of total 46-60 Gy/23-30 fraction, 2 had partial cranial radiotherapy of 50 Gy/25 fraction.
RESULTS: 5 of our patients currently survive disease-free, 9 are excitus, 6 had no disease-free survival, and 8 had an average disease free survival of 26 months. The mean survival is 19.7 mounths (3-55 months). lf the patients condition is appropriate, partial cranial radiotherapy yields the longest disease-free and total survival times. (The mean disease-free survival is 38.5 months and the total survival is 41 months)
Keywords: Oligodendroglioma, radiotherapy, surgery.
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