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2 - Preoperative evaluation of doppler ultrasound indices in postmenopausal ovarian masses
Burçin Demirel, Veli Mihmanlı, Gözde Toprakçı, Mehmet Fatih Fındık, Orhan Özen, Fatih Kantarcı
Objective: The aim of this study was to evaluate the value of quantitative spectral Doppler ultrasound (DUS) flow measurements in ovarian tumors in postmenopausal women.
Material and Method: This prospective study included 23 postmenopausal women with preoperative diagnosis of ovarian tumor. Patients were examined with transvaginal DUS 2 to 4 days before surgery. The resistive index (RI) and pulsatility index (PI) of the mass were evaluated by transvaginal DUS examination.
Results: The histopathologic examination of the surgical specimens revealed 8 malignant, 13 benign and 1 borderline tumor. The mean RI and PI for malignant tumors were 0.37 (range 0.35-0.45) and 0.61 (range 0.43-0.85), respectively. The mean RI and PI for benign tumors were 0.61 (range 0.30-0.91) and 1.21 (range 0.36-3.02), respectively. The Mann-Whitney U test revealed a statistically significant (p<0.05) correlation between the DUS measurements and histopathologic results. The sensitivity, specificity, positive and negative predictive cut-off values for RI less than 0.4 was 77%, 85%, 77%, and 85% respectively, in the diagnosis of malignant lesions. The sensitivity, specificity, positive and negative predictive cut-off values for PI less than 0.7 was 77%, 78% 70%, and 84% respectively.
Conclusion: Quantitative transvaginal DUS flow measurements provides sensitive and specific results in differentiating benign from malignant ovarian tumors in postmenopausal women.
Keywords: Ovarian neoplasm, benign, malignant, doppler ultrasound, resistive index, pulsatility index
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