The publication of University of Health Sciences, Istanbul Sisli Hamidiye Etfal Medical Practice and Research Center

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          VOLUME 45 / ISSUE 3

The Journal is Indexed in

2 - Investigation of the immunological changes and comparison of the microbiological flora of the tonsil surface and core in recurrent tonsillitis

Erdoğan Gültekin, Ömer N. Develioğlu, Murat Yener, Mehmet Karakaya, Zafer Çiftçi

Objective: To compare the microbiologic flora from the surface and core cultures in patients with recurrent tonsillitis and to study the immunologic changes within the tonsils.

Material and Methods: Forty – two patients, who were treated by tonsillectomy for recurrent tonsillitis in Taksim Research and Training Hospital Otorhinolaryngology Department, were enrolled in this study. After intubation and following oropharyngeal aspiration, tonsillar surface cultures were taken transorally. Following tonsillectomy, each tonsil was divided into two using a scalpel and tonsil core cultures were taken for microbiological analysis. The other half of the tonsils were sent to pathology laboratory for histopahological evaluation.

Results: The most frequent bacterium isolated from the samples was beta hemolytic streptococcus. When surface and core cultures of the tonsils were compared, no statistically significant difference was observed in the incidence of beta hemolytic streptococcus and alpha hemolytic streptococcus isolation (p>0.05). Detection of pathogenic microorganism in the core cultures was significantly higher than the surface cultures (p<0.05). In the germinal center mean B cell count was 79.35±11.68 and mean T cell count was 4.82±4.92. The difference of B and T cell counts was statistically significant (p<0,0001).

Conclusion: Surface cultures may be unable to detect the real pathogens in cases with recurrent tonsillitis.

Keywords: Recurrent tonsillitis, core culture, surface culture

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